Version 5.4
Homo sapiens Protein: MLL3
Summary
InnateDB Protein IDBP-387471.4
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol MLL3
Protein Name myeloid/lymphoid or mixed-lineage leukemia 3
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000410411
InnateDB Gene IDBG-49771 (MLL3)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 32 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
Experimentally validated
Total 32 [view]
Protein-Protein 32 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 2 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0008168 methyltransferase activity
GO:0008270 zinc ion binding
Biological Process
GO:0032259 methylation
Cellular Component
GO:0005634 nucleus
Protein Structure and Domains
PDB ID
InterPro IPR001214 SET domain
IPR003616 Post-SET domain
IPR003888 FY-rich, N-terminal
IPR003889 FY-rich, C-terminal
IPR011011 Zinc finger, FYVE/PHD-type
PFAM PF00856
PF05964
PF05965
PRINTS
PIRSF
SMART SM00317
SM00508
SM00541
SM00542
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL Q6N019
UniProt Splice Variant
Entrez Gene 58508
UniGene Hs.649297
RefSeq
HUGO HGNC:13726
OMIM 606833
CCDS
HPRD 06016
IMGT
EMBL AC005631 AC006017 AC006474 AC104692 BX640742
GenPept CAE45854

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca