InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: ADCY4

Summary

InnateDB Protein

IDBP-3878.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

ADCY4

Protein Name

adenylate cyclase 4

Synonyms

Species

Homo sapiens

Ensembl Protein

ENSP00000312126

InnateDB Gene

IDBG-3876 (ADCY4)

Protein Structure

UniProt Annotation

Function

This is a membrane-bound, calmodulin-insensitive adenylyl cyclase. {ECO:0000250}.

Subcellular Localization

Membrane; Multi-pass membrane protein.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004016	adenylate cyclase activity
GO:0005515	protein binding
GO:0005524	ATP binding
GO:0016849	phosphorus-oxygen lyase activity
GO:0046872	metal ion binding

Biological Process

GO:0006112	energy reserve metabolic process
GO:0006171	cAMP biosynthetic process
GO:0006833	water transport
GO:0007165	signal transduction
GO:0007173	epidermal growth factor receptor signaling pathway
GO:0007188	adenylate cyclase-modulating G-protein coupled receptor signaling pathway
GO:0007189	adenylate cyclase-activating G-protein coupled receptor signaling pathway
GO:0007193	adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway
GO:0007202	activation of phospholipase C activity
GO:0007268	synaptic transmission
GO:0008543	fibroblast growth factor receptor signaling pathway
GO:0009190	cyclic nucleotide biosynthetic process
GO:0034199	activation of protein kinase A activity
GO:0035556	intracellular signal transduction
GO:0044281	small molecule metabolic process
GO:0045087	innate immune response
GO:0048011	neurotrophin TRK receptor signaling pathway
GO:0055085	transmembrane transport
GO:0071377	cellular response to glucagon stimulus