Version 5.4
Homo sapiens Protein: SCAF8
Summary
InnateDB Protein IDBP-388003.4
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol SCAF8
Protein Name SR-related CTD-associated factor 8
Synonyms RBM16;
Species Homo sapiens
Ensembl Protein ENSP00000413098
InnateDB Gene IDBG-246149 (SCAF8)
Protein Structure
UniProt Annotation
Function May play a role in mRNA processing. {ECO:0000269PubMed:11101529}.
Subcellular Localization Nucleus. Nucleus matrix. Note=Detected in granular nuclear foci which correspond to sites of active transcription. {ECO:0000250}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 27 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 27 [view]
Protein-Protein 20 [view]
Protein-DNA 7 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0000166 nucleotide binding
GO:0003676 nucleic acid binding
GO:0003723 RNA binding
GO:0043175 RNA polymerase core enzyme binding
Biological Process
GO:0006397 mRNA processing
GO:0008380 RNA splicing
Cellular Component
GO:0005634 nucleus
GO:0005681 spliceosomal complex
GO:0016363 nuclear matrix
Protein Structure and Domains
PDB ID
InterPro IPR000504 RNA recognition motif domain
IPR006569 CID domain
IPR006903 RNA polymerase II-binding domain
IPR008942 ENTH/VHS
PFAM PF00076
PF04818
PRINTS
PIRSF
SMART SM00360
SM00582
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q9UPN6
PhosphoSite PhosphoSite-Q9UPN6
TrEMBL Q9H8B2
UniProt Splice Variant
Entrez Gene 22828
UniGene Hs.603396
RefSeq NP_001273123
HUGO HGNC:20959
OMIM
CCDS CCDS75541
HPRD 11487
IMGT
EMBL AB029039 AK023859 AL121952 AL136976 AL591499 AL833928 BC070071
GenPept AAH70071 BAA83068 BAB14705 CAD38784 CAH70694 CAI21474 CAI21482

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca