Homo sapiens Protein: ALS2
Summary
InnateDB Protein IDBP-388386.4
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol ALS2
Protein Name amyotrophic lateral sclerosis 2 (juvenile)
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000403832
InnateDB Gene IDBG-78753 (ALS2)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 12 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 12 [view]
Protein-Protein 8 [view]
Protein-DNA 4 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005089 Rho guanyl-nucleotide exchange factor activity
Biological Process
GO:0032321 positive regulation of Rho GTPase activity
GO:0035023 regulation of Rho protein signal transduction
Cellular Component
Protein Structure and Domains
PDB ID
InterPro IPR000219 Dbl homology (DH) domain
IPR003409 MORN motif
PFAM PF00621
PF02493
PRINTS
PIRSF
SMART SM00325
SM00698
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL B3KPJ0
UniProt Splice Variant
Entrez Gene 57679
UniGene Hs.621812
RefSeq
HUGO HGNC:443
OMIM 606352
CCDS
HPRD 05893
IMGT
EMBL AC007242 AC007279 AK056413
GenPept BAG51702