InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: VIL1

Summary

InnateDB Protein

IDBP-388905.4

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

VIL1

Protein Name

villin 1

Synonyms

D2S1471; VIL;

Species

Homo sapiens

Ensembl Protein

ENSP00000409270

InnateDB Gene

IDBG-80992 (VIL1)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 7 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.

Experimentally validated
Total	7 [view]
Protein-Protein	7 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	3 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003779	actin binding
GO:0005509	calcium ion binding
GO:0005515	protein binding
GO:0005546	phosphatidylinositol-4,5-bisphosphate binding
GO:0035727	lysophosphatidic acid binding
GO:0042802	identical protein binding
GO:0042803	protein homodimerization activity
GO:0043027	cysteine-type endopeptidase inhibitor activity involved in apoptotic process
GO:0051015	actin filament binding

Biological Process

GO:0006461	protein complex assembly
GO:0007173	epidermal growth factor receptor signaling pathway
GO:0008360	regulation of cell shape
GO:0009617	response to bacterium
GO:0010634	positive regulation of epithelial cell migration
GO:0030041	actin filament polymerization
GO:0030042	actin filament depolymerization
GO:0030335	positive regulation of cell migration
GO:0030855	epithelial cell differentiation
GO:0032233	positive regulation of actin filament bundle assembly
GO:0051014	actin filament severing
GO:0051125	regulation of actin nucleation
GO:0051693	actin filament capping
GO:0060327	cytoplasmic actin-based contraction involved in cell motility
GO:0061041	regulation of wound healing
GO:0071364	cellular response to epidermal growth factor stimulus
GO:2000392	regulation of lamellipodium morphogenesis

Cellular Component

GO:0001726	ruffle
GO:0005737	cytoplasm
GO:0005902	microvillus
GO:0030027	lamellipodium
GO:0030175	filopodium
GO:0032432	actin filament bundle
GO:0032433	filopodium tip
GO:0070062	extracellular vesicular exosome