InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: PTPRN

Summary

InnateDB Protein

IDBP-389059.4

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

PTPRN

Protein Name

protein tyrosine phosphatase, receptor type, N

Synonyms

IA-2; IA-2/PTP; IA2; ICA512; R-PTP-N;

Species

Homo sapiens

Ensembl Protein

ENSP00000392598

InnateDB Gene

IDBG-81527 (PTPRN)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 8 experimentally validated interaction(s) in this database.

Experimentally validated
Total	8 [view]
Protein-Protein	8 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004725	protein tyrosine phosphatase activity
GO:0005001	transmembrane receptor protein tyrosine phosphatase activity
GO:0005515	protein binding
GO:0016791	phosphatase activity
GO:0030507	spectrin binding

Biological Process

GO:0000302	response to reactive oxygen species
GO:0006470	protein dephosphorylation
GO:0016311	dephosphorylation
GO:0035335	peptidyl-tyrosine dephosphorylation

Cellular Component

GO:0005887

integral component of plasma membrane

Protein Structure and Domains

PDB ID

InterPro

IPR000242 Protein-tyrosine phosphatase, receptor/non-receptor type
IPR000387 Protein-tyrosine/Dual specificity phosphatase
IPR003595 Protein-tyrosine phosphatase, catalytic
IPR021613 Protein-tyrosine phosphatase receptor IA-2 ectodomain
IPR029021 Protein-tyrosine phosphatase-like

PFAM

PF00102
PF11548

PRINTS

PR00700

PIRSF

SMART

SM00194
SM00404

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt