Version 5.4
Homo sapiens Protein: CUL3
Summary
InnateDB Protein IDBP-389146.4
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol CUL3
Protein Name cullin 3
Synonyms CUL-3; PHA2E;
Species Homo sapiens
Ensembl Protein ENSP00000410575
InnateDB Gene IDBG-82331 (CUL3)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1215 experimentally validated interaction(s) in this database.
They are also associated with 28 interaction(s) predicted by orthology.
Experimentally validated
Total 1215 [view]
Protein-Protein 1215 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 28 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0031625 ubiquitin protein ligase binding
Biological Process
GO:0006511 ubiquitin-dependent protein catabolic process
Cellular Component
GO:0031461 cullin-RING ubiquitin ligase complex
Protein Structure and Domains
PDB ID
InterPro IPR001373 Cullin, N-terminal
IPR016158 Cullin homology
IPR019559 Cullin protein, neddylation domain
PFAM PF00888
PF10557
PRINTS
PIRSF
SMART SM00182
SM00884
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL
UniProt Splice Variant
Entrez Gene 8452
UniGene Hs.594397
RefSeq
HUGO HGNC:2553
OMIM 603136
CCDS
HPRD 09123
IMGT
EMBL
GenPept

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca