InnateDB Protein
|
IDBP-38989.7
|
Last Modified
|
2014-10-13 [Report errors or provide feedback]
|
Gene Symbol
|
CAPRIN1
|
Protein Name
|
cell cycle associated protein 1
|
Synonyms
|
GPIAP1; GPIP137; GRIP137; M11S1; p137GPI; RNG105;
|
Species
|
Homo sapiens
|
Ensembl Protein
|
ENSP00000374296
|
InnateDB Gene
|
IDBG-38977 (CAPRIN1)
|
Protein Structure
|
|
Function |
May regulate the transport and translation of mRNAs of proteins involved in synaptic plasticity in neurons and cell proliferation and migration in multiple cell types. {ECO:0000250}.
|
Subcellular Localization |
Cytoplasm, cytosol. Cell projection, dendrite. Note=Associated with RNA granules. {ECO:0000250}.
|
Disease Associations |
|
Tissue Specificity |
Ubiquitous.
|
Comments |
|
Number of Interactions
|
This gene and/or its encoded proteins are associated with 36 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
Experimentally validated |
Total |
36
[view]
|
Protein-Protein |
36
[view]
|
Protein-DNA |
0
|
Protein-RNA |
0
|
DNA-DNA |
0
|
RNA-RNA |
0
|
DNA-RNA |
0
|
|
Predicted by orthology |
Total |
2 [view]
|
|
|
Molecular Function |
|
Biological Process |
GO:0017148
|
negative regulation of translation
|
GO:0050775
|
positive regulation of dendrite morphogenesis
|
GO:0061003
|
positive regulation of dendritic spine morphogenesis
|
|
Cellular Component |
|
PDB ID |
|
InterPro |
IPR022070
Cytoplasmic activation/proliferation-associated protein-1 C term
|
PFAM |
PF12287
|
PRINTS |
|
PIRSF |
|
SMART |
|
TIGRFAMs |
|
Modification |
|
SwissProt |
Q14444
|
PhosphoSite |
PhosphoSite-Q14444
|
TrEMBL |
E9PLA9
|
UniProt Splice Variant |
|
Entrez Gene |
4076
|
UniGene |
Hs.717895
|
RefSeq |
NP_976240
|
HUGO |
HGNC:6743
|
OMIM |
601178
|
CCDS |
CCDS31454
|
HPRD |
03108
|
IMGT |
|
EMBL |
AC090469
BC001731
BK001101
BK001104
BR000867
CH471064
X89572
Z48042
|
GenPept |
AAH01731
CAA61751
CAA88096
DAA01118
DAA01121
EAW68177
EAW68178
EAW68179
FAA00692
|
|
|