Version 5.4
Homo sapiens Protein: KCNK2
Summary
InnateDB Protein IDBP-390018.4
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol KCNK2
Protein Name potassium channel, subfamily K, member 2
Synonyms hTREK-1c; hTREK-1e; K2p2.1; TPKC1; TREK; TREK-1; TREK1;
Species Homo sapiens
Ensembl Protein ENSP00000413460
InnateDB Gene IDBG-106654 (KCNK2)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 1 [view]
Protein-Protein 0
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005216 ion channel activity
Biological Process
GO:0006811 ion transport
GO:0055085 transmembrane transport
GO:0071805 potassium ion transmembrane transport
Cellular Component
GO:0016020 membrane
Protein Structure and Domains
PDB ID
InterPro IPR003976 Two pore domain potassium channel, TREK
IPR005821 Ion transport domain
IPR013099 Two pore domain potassium channel domain
PFAM PF00520
PF07885
PRINTS PR01499
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL C9JXY2
UniProt Splice Variant
Entrez Gene 3776
UniGene Hs.497745
RefSeq
HUGO HGNC:6277
OMIM 603219
CCDS
HPRD
IMGT
EMBL AC092804 AC099675 AL583830
GenPept

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca