InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: PPP2R3B

Summary

InnateDB Protein

IDBP-39011.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

PPP2R3B

Protein Name

protein phosphatase 2, regulatory subunit B'', beta

Synonyms

Species

Homo sapiens

Ensembl Protein

ENSP00000375080

InnateDB Gene

IDBG-39003 (PPP2R3B)

Protein Structure

UniProt Annotation

Function

The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment.

Subcellular Localization

Nucleus {ECO:0000269PubMed:10629059}.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 13 experimentally validated interaction(s) in this database.

Experimentally validated
Total	13 [view]
Protein-Protein	13 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004721	phosphoprotein phosphatase activity
GO:0004722	protein serine/threonine phosphatase activity
GO:0005509	calcium ion binding
GO:0005515	protein binding
GO:0008601	protein phosphatase type 2A regulator activity

Biological Process

GO:0000082	G1/S transition of mitotic cell cycle
GO:0000278	mitotic cell cycle
GO:0006470	protein dephosphorylation
GO:0007050	cell cycle arrest
GO:0050790	regulation of catalytic activity