Version 5.4
Homo sapiens Protein: SUGP1
Summary
InnateDB Protein IDBP-39756.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol SUGP1
Protein Name SURP and G patch domain containing 1
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000247001
InnateDB Gene IDBG-39752 (SUGP1)
Protein Structure
UniProt Annotation
Function Plays a role in pre-mRNA splicing.
Subcellular Localization Nucleus {ECO:0000305}.
Disease Associations
Tissue Specificity Detected in adult testis and heart, and in adult and fetal brain, kidney and skeletal muscle. {ECO:0000269PubMed:12594045}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 51 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 51 [view]
Protein-Protein 51 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003676 nucleic acid binding
GO:0003723 RNA binding
GO:0005515 protein binding
GO:0044822 poly(A) RNA binding
Biological Process
GO:0000398 mRNA splicing, via spliceosome
GO:0006396 RNA processing
GO:0008380 RNA splicing
GO:0010467 gene expression
Cellular Component
GO:0005654 nucleoplasm
GO:0005681 spliceosomal complex
Protein Structure and Domains
PDB ID
InterPro IPR000061 SWAP/Surp
IPR000467 G-patch domain
PFAM PF01805
PF01585
PRINTS
PIRSF
SMART SM00648
SM00443
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q8IWZ8
PhosphoSite PhosphoSite-Q8IWZ8
TrEMBL K7ESM0
UniProt Splice Variant
Entrez Gene 57794
UniGene Hs.515274
RefSeq NP_757386
HUGO HGNC:18643
OMIM 607992
CCDS CCDS12399
HPRD 10468
IMGT
EMBL AC003967 AC004475 AC022543 AF521128 AK092745 AL137286 AL713757 AY072916 AY072917 BC063784 CH471106
GenPept AAC08052 AAH63784 AAL68960 AAL68961 AAN77123 BAG52606 CAB70678 CAD28528 EAW84808 EAW84811 EAW84812

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca