InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Por

Summary

InnateDB Protein

IDBP-400169.4

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Por

Protein Name

P450 (cytochrome) oxidoreductase

Synonyms

4933424M13Rik; CPR; CYPOR;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000112924

InnateDB Gene

IDBG-204005 (Por)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 15 experimentally validated interaction(s) in this database.
They are also associated with 13 interaction(s) predicted by orthology.

Experimentally validated
Total	15 [view]
Protein-Protein	14 [view]
Protein-DNA	1 [view]
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	13 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003958	NADPH-hemoprotein reductase activity
GO:0004128	cytochrome-b5 reductase activity, acting on NAD(P)H
GO:0005506	iron ion binding
GO:0008941	nitric oxide dioxygenase activity
GO:0009055	electron carrier activity
GO:0010181	FMN binding
GO:0016491	oxidoreductase activity
GO:0016709	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen
GO:0016787	hydrolase activity
GO:0019899	enzyme binding
GO:0047726	iron-cytochrome-c reductase activity
GO:0050660	flavin adenine dinucleotide binding
GO:0050661	NADP binding

Biological Process

GO:0003420	regulation of growth plate cartilage chondrocyte proliferation
GO:0007584	response to nutrient
GO:0009437	carnitine metabolic process
GO:0009812	flavonoid metabolic process
GO:0018393	internal peptidyl-lysine acetylation
GO:0019395	fatty acid oxidation
GO:0032332	positive regulation of chondrocyte differentiation
GO:0032770	positive regulation of monooxygenase activity
GO:0042493	response to drug
GO:0043066	negative regulation of apoptotic process
GO:0043154	negative regulation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0043602	nitrate catabolic process
GO:0045542	positive regulation of cholesterol biosynthetic process
GO:0045880	positive regulation of smoothened signaling pathway
GO:0046210	nitric oxide catabolic process
GO:0055114	oxidation-reduction process
GO:0060192	negative regulation of lipase activity
GO:0070988	demethylation
GO:0071372	cellular response to follicle-stimulating hormone stimulus
GO:0071375	cellular response to peptide hormone stimulus
GO:0090031	positive regulation of steroid hormone biosynthetic process
GO:0090346	cellular organofluorine metabolic process

Cellular Component

GO:0005739	mitochondrion
GO:0005829	cytosol
GO:0016020	membrane

Protein Structure and Domains

PDB ID

MGI:97744

InterPro

IPR001094 Flavodoxin
IPR001433 Oxidoreductase FAD/NAD(P)-binding
IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase
IPR003097 FAD-binding, type 1
IPR008254 Flavodoxin/nitric oxide synthase
IPR017938 Riboflavin synthase-like beta-barrel
IPR029039 Flavoprotein-like

PFAM

PF00175
PF00667
PF00258

PRINTS

PR00369
PR00371

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite

PhosphoSite-

TrEMBL

Q3V2F8

UniProt Splice Variant

Entrez Gene

18984

UniGene

Mm.488967

RefSeq

MGI ID

MGI Symbol

Por

OMIM

CCDS

HPRD

IMGT

EMBL

AC083948 AK131867 BC003240

GenPept

AAH03240 BAE20840