InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Psph

Summary

InnateDB Protein

IDBP-400230.4

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Psph

Protein Name

phosphoserine phosphatase

Synonyms

AI480570; PSP; PSPase;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000113671

InnateDB Gene

IDBG-202016 (Psph)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.
They are also associated with 15 interaction(s) predicted by orthology.

Experimentally validated
Total	3 [view]
Protein-Protein	3 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	15 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0000287	magnesium ion binding
GO:0004647	phosphoserine phosphatase activity
GO:0005509	calcium ion binding
GO:0016791	phosphatase activity
GO:0042803	protein homodimerization activity

Biological Process

GO:0006564	L-serine biosynthetic process
GO:0008152	metabolic process
GO:0009612	response to mechanical stimulus
GO:0016311	dephosphorylation
GO:0031667	response to nutrient levels
GO:0033574	response to testosterone

Cellular Component

GO:0005737	cytoplasm
GO:0043005	neuron projection

Protein Structure and Domains

PDB ID

MGI:97788

InterPro

IPR006383 HAD-superfamily hydrolase, subfamily IB, PSPase-like
IPR023214 HAD-like domain

PFAM

PF00702
PF08282
PF13419

PRINTS

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite

PhosphoSite-

TrEMBL

D3Z666

UniProt Splice Variant

Entrez Gene

100678

UniGene

Mm.271784

RefSeq

MGI ID

MGI Symbol

Psph

OMIM

CCDS

HPRD

IMGT

EMBL

AC186296 CAAA01206539 CH466529

GenPept

EDL19501