Version 5.4
Mus musculus Protein: Vamp2
Summary
InnateDB Protein IDBP-400320.4
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Vamp2
Protein Name vesicle-associated membrane protein 2
Synonyms Syb-2; Syb2; sybII;
Species Mus musculus
Ensembl Protein ENSMUSP00000112611
InnateDB Gene IDBG-189759 (Vamp2)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 32 experimentally validated interaction(s) in this database.
Experimentally validated
Total 32 [view]
Protein-Protein 31 [view]
Protein-DNA 0
Protein-RNA 1 [view]
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0000149 SNARE binding
GO:0005484 SNAP receptor activity
GO:0005515 protein binding
GO:0005516 calmodulin binding
GO:0005543 phospholipid binding
GO:0017075 syntaxin-1 binding
Biological Process
GO:0006906 vesicle fusion
GO:0016079 synaptic vesicle exocytosis
GO:0016192 vesicle-mediated transport
GO:0017156 calcium ion-dependent exocytosis
GO:0017157 regulation of exocytosis
GO:0032869 cellular response to insulin stimulus
GO:0043001 Golgi to plasma membrane protein transport
GO:0060291 long-term synaptic potentiation
GO:0060627 regulation of vesicle-mediated transport
GO:0061025 membrane fusion
GO:0090316 positive regulation of intracellular protein transport
Cellular Component
GO:0005886 plasma membrane
GO:0008021 synaptic vesicle
GO:0016020 membrane
GO:0016021 integral component of membrane
GO:0030141 secretory granule
GO:0030672 synaptic vesicle membrane
GO:0031410 cytoplasmic vesicle
GO:0042589 zymogen granule membrane
GO:0045202 synapse
GO:0070032 synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex
GO:0070044 synaptobrevin 2-SNAP-25-syntaxin-1a complex
Protein Structure and Domains
PDB ID MGI:1313277
InterPro IPR001388 Synaptobrevin
PFAM PF00957
PRINTS PR00219
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL B0QZN5
UniProt Splice Variant
Entrez Gene 22318
UniGene Mm.418428
RefSeq
MGI ID
MGI Symbol Vamp2
OMIM
CCDS
HPRD
IMGT
EMBL AL645527
GenPept

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca