Version 5.4
Mus musculus Protein: Nlgn3
Summary
InnateDB Protein IDBP-400704.4
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Nlgn3
Protein Name neuroligin 3
Synonyms
Species Mus musculus
Ensembl Protein ENSMUSP00000113863
InnateDB Gene IDBG-163514 (Nlgn3)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 6 interaction(s) predicted by orthology.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 6 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004872 receptor activity
GO:0016787 hydrolase activity
GO:0042043 neurexin family protein binding
Biological Process
GO:0002087 regulation of respiratory gaseous exchange by neurological system process
GO:0007155 cell adhesion
GO:0007416 synapse assembly
GO:0008152 metabolic process
GO:0008542 visual learning
GO:0030534 adult behavior
GO:0035176 social behavior
GO:0048709 oligodendrocyte differentiation
GO:0050804 regulation of synaptic transmission
GO:0050808 synapse organization
GO:0060080 regulation of inhibitory postsynaptic membrane potential
GO:0071625 vocalization behavior
Cellular Component
GO:0005737 cytoplasm
GO:0005887 integral component of plasma membrane
GO:0009986 cell surface
GO:0045202 synapse
GO:0060076 excitatory synapse
Protein Structure and Domains
PDB ID MGI:2444609
InterPro IPR000460 Neuroligin
IPR002018 Carboxylesterase, type B
IPR013094 Alpha/beta hydrolase fold-3
IPR029058 Alpha/Beta hydrolase fold
PFAM PF00135
PF07859
PRINTS PR01090
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL Q924X0
UniProt Splice Variant
Entrez Gene 245537
UniGene Mm.490139
RefSeq
MGI ID
MGI Symbol Nlgn3
OMIM
CCDS
HPRD
IMGT
EMBL AJ291730 AL683892
GenPept CAC37694

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca