InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Ttc3

Summary

InnateDB Protein

IDBP-400803.4

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Ttc3

Protein Name

tetratricopeptide repeat domain 3

Synonyms

2610202A04Rik; AA409221; D16Ium21; D16Ium21e; mKIAA4119; TPRD;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000112801

InnateDB Gene

IDBG-178662 (Ttc3)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 5 experimentally validated interaction(s) in this database.
They are also associated with 10 interaction(s) predicted by orthology.

Experimentally validated
Total	5 [view]
Protein-Protein	4 [view]
Protein-DNA	1 [view]
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	10 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004842	ubiquitin-protein transferase activity
GO:0005515	protein binding
GO:0008270	zinc ion binding
GO:0046872	metal ion binding

Biological Process

GO:0006511	ubiquitin-dependent protein catabolic process
GO:0010771	negative regulation of cell morphogenesis involved in differentiation
GO:0045665	negative regulation of neuron differentiation
GO:0070936	protein K48-linked ubiquitination

Cellular Component

GO:0005634	nucleus
GO:0005739	mitochondrion
GO:0005773	vacuole

Protein Structure and Domains

PDB ID

MGI:1276539

InterPro

IPR001841 Zinc finger, RING-type
IPR011029 Death-like domain
IPR013026 Tetratricopeptide repeat-containing domain
IPR018957 Zinc finger, C3HC4 RING-type
IPR019734 Tetratricopeptide repeat

PFAM

PF13639
PF14634
PF00097
PF13174
PF13176
PF13181

PRINTS

PIRSF

SMART

SM00184
SM00028

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite