InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Robo2

Summary

InnateDB Protein

IDBP-400965.4

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Robo2

Protein Name

roundabout homolog 2 (Drosophila)

Synonyms

Species

Mus musculus

Ensembl Protein

ENSMUSP00000112776

InnateDB Gene

IDBG-171179 (Robo2)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 14 interaction(s) predicted by orthology.

Predicted by orthology
Total	14 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005515	protein binding
GO:0008046	axon guidance receptor activity
GO:0042802	identical protein binding
GO:0046982	protein heterodimerization activity

Biological Process

GO:0001656	metanephros development
GO:0001657	ureteric bud development
GO:0007156	homophilic cell adhesion
GO:0007411	axon guidance
GO:0007420	brain development
GO:0021510	spinal cord development
GO:0032870	cellular response to hormone stimulus
GO:0050772	positive regulation of axonogenesis
GO:0050925	negative regulation of negative chemotaxis
GO:0061364	apoptotic process involved in luteolysis

Cellular Component

GO:0009986	cell surface
GO:0030673	axolemma
GO:0070062	extracellular vesicular exosome

Protein Structure and Domains

PDB ID

MGI:1890110

InterPro

IPR003596 Immunoglobulin V-set, subgroup
IPR003598 Immunoglobulin subtype 2
IPR003599 Immunoglobulin subtype
IPR003961 Fibronectin, type III
IPR007110 Immunoglobulin-like domain
IPR013098 Immunoglobulin I-set
IPR013106 Immunoglobulin V-set domain
IPR013151 Immunoglobulin

PFAM

PF00041
PF01108
PF07679
PF07686
PF00047

PRINTS

PIRSF

SMART

SM00406
SM00408
SM00409
SM00060

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite