InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Gata4

Summary

InnateDB Protein

IDBP-401051.4

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Gata4

Protein Name

GATA binding protein 4

Synonyms

Gata-4;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000113891

InnateDB Gene

IDBG-172452 (Gata4)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 47 experimentally validated interaction(s) in this database.
They are also associated with 30 interaction(s) predicted by orthology.

Experimentally validated
Total	47 [view]
Protein-Protein	34 [view]
Protein-DNA	13 [view]
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	30 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0000977	RNA polymerase II regulatory region sequence-specific DNA binding
GO:0000978	RNA polymerase II core promoter proximal region sequence-specific DNA binding
GO:0000981	sequence-specific DNA binding RNA polymerase II transcription factor activity
GO:0001076	RNA polymerase II transcription factor binding transcription factor activity
GO:0001158	enhancer sequence-specific DNA binding
GO:0003677	DNA binding
GO:0003682	chromatin binding
GO:0003700	sequence-specific DNA binding transcription factor activity
GO:0003705	RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity
GO:0005515	protein binding
GO:0008270	zinc ion binding
GO:0033613	activating transcription factor binding
GO:0043565	sequence-specific DNA binding
GO:0044212	transcription regulatory region DNA binding
GO:0051525	NFAT protein binding
GO:0070410	co-SMAD binding

Biological Process

GO:0001701	in utero embryonic development
GO:0001702	gastrulation with mouth forming second
GO:0001706	endoderm formation
GO:0001947	heart looping
GO:0003007	heart morphogenesis
GO:0003151	outflow tract morphogenesis
GO:0003181	atrioventricular valve morphogenesis
GO:0003190	atrioventricular valve formation
GO:0003192	mitral valve formation
GO:0003195	tricuspid valve formation
GO:0003197	endocardial cushion development
GO:0003215	cardiac right ventricle morphogenesis
GO:0003229	ventricular cardiac muscle tissue development
GO:0003279	cardiac septum development
GO:0003281	ventricular septum development
GO:0003289	atrial septum primum morphogenesis
GO:0003290	atrial septum secundum morphogenesis
GO:0006355	regulation of transcription, DNA-templated
GO:0006357	regulation of transcription from RNA polymerase II promoter
GO:0006366	transcription from RNA polymerase II promoter
GO:0007267	cell-cell signaling
GO:0007283	spermatogenesis
GO:0007507	heart development
GO:0009612	response to mechanical stimulus
GO:0010468	regulation of gene expression
GO:0010507	negative regulation of autophagy
GO:0010575	positive regulation vascular endothelial growth factor production
GO:0014898	cardiac muscle hypertrophy in response to stress
GO:0023019	signal transduction involved in regulation of gene expression
GO:0030509	BMP signaling pathway
GO:0030513	positive regulation of BMP signaling pathway
GO:0032526	response to retinoic acid
GO:0035050	embryonic heart tube development
GO:0035054	embryonic heart tube anterior/posterior pattern specification
GO:0035239	tube morphogenesis
GO:0035914	skeletal muscle cell differentiation
GO:0036302	atrioventricular canal development
GO:0042493	response to drug
GO:0043627	response to estrogen
GO:0045087	innate immune response (InnateDB)
GO:0045766	positive regulation of angiogenesis
GO:0045893	positive regulation of transcription, DNA-templated
GO:0045944	positive regulation of transcription from RNA polymerase II promoter
GO:0048557	embryonic digestive tract morphogenesis
GO:0048598	embryonic morphogenesis
GO:0048617	embryonic foregut morphogenesis
GO:0048738	cardiac muscle tissue development
GO:0051891	positive regulation of cardioblast differentiation
GO:0055007	cardiac muscle cell differentiation
GO:0060008	Sertoli cell differentiation
GO:0060043	regulation of cardiac muscle cell proliferation
GO:0060045	positive regulation of cardiac muscle cell proliferation
GO:0060070	canonical Wnt signaling pathway
GO:0060395	SMAD protein signal transduction
GO:0060425	lung morphogenesis
GO:0060464	lung lobe formation
GO:0060540	diaphragm morphogenesis
GO:0060575	intestinal epithelial cell differentiation
GO:0060979	vasculogenesis involved in coronary vascular morphogenesis
GO:0061049	cell growth involved in cardiac muscle cell development
GO:0071333	cellular response to glucose stimulus
GO:0071371	cellular response to gonadotropin stimulus
GO:0071372	cellular response to follicle-stimulating hormone stimulus
GO:0072148	epithelial cell fate commitment
GO:0072520	seminiferous tubule development
GO:0086004	regulation of cardiac muscle cell contraction