InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Lancl1

Summary

InnateDB Protein

IDBP-401156.4

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Lancl1

Protein Name

LanC (bacterial lantibiotic synthetase component C)-like 1

Synonyms

AW124738; Gpr69; Gpr69a; p40;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000113080

InnateDB Gene

IDBG-163777 (Lancl1)

Protein Structure

UniProt Annotation

Function

May play a role in EPS8 signaling. Binds glutathione (By similarity). {ECO:0000250}.

Subcellular Localization

Cytoplasm {ECO:0000250}. Membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}. Nucleus {ECO:0000250}.

Disease Associations

Tissue Specificity

Detected in spinal cord (at protein level). Ubiquitous. Strongly expressed in brain, testis, alveolar macrophages and epithelial cells of the lung, kidney and intestine. {ECO:0000269PubMed:17305318, ECO:0000269PubMed:9714732}.

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
They are also associated with 5 interaction(s) predicted by orthology.

Experimentally validated
Total	2 [view]
Protein-Protein	2 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	5 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003824	catalytic activity
GO:0008270	zinc ion binding
GO:0017124	SH3 domain binding
GO:0043295	glutathione binding
GO:0050750	low-density lipoprotein particle receptor binding