InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Il12rb2

Summary

InnateDB Protein

IDBP-401173.4

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Il12rb2

Protein Name

interleukin 12 receptor, beta 2

Synonyms

A930027I18Rik; Ifnm; IL-12RB2;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000113267

InnateDB Gene

IDBG-153874 (Il12rb2)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 10 experimentally validated interaction(s) in this database.
They are also associated with 6 interaction(s) predicted by orthology.

Experimentally validated
Total	10 [view]
Protein-Protein	5 [view]
Protein-DNA	5 [view]
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	6 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004896	cytokine receptor activity
GO:0005515	protein binding
GO:0019901	protein kinase binding

Biological Process

GO:0018108	peptidyl-tyrosine phosphorylation
GO:0019221	cytokine-mediated signaling pathway
GO:0032496	response to lipopolysaccharide
GO:0032609	interferon-gamma production
GO:0034097	response to cytokine

Cellular Component

GO:0009897

external side of plasma membrane

Protein Structure and Domains

PDB ID

MGI:1270861

InterPro

IPR003961 Fibronectin, type III

PFAM

PF00041
PF01108

PRINTS

PIRSF

SMART

SM00060

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite

PhosphoSite-

TrEMBL

D3Z6H5

UniProt Splice Variant

Entrez Gene

16162

UniGene

Mm.188337

RefSeq

MGI ID

MGI Symbol

Il12rb2

OMIM

CCDS

HPRD

IMGT

EMBL

AC130822

GenPept