InnateDB Protein
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IDBP-401216.4
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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Pld3
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Protein Name
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phospholipase D family, member 3
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Synonyms
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Sam-9;
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Species
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Mus musculus
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Ensembl Protein
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ENSMUSP00000112942
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InnateDB Gene
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IDBG-161294 (Pld3)
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Protein Structure
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|
Function |
Probably involved in APP processing. {ECO:0000250}.
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Subcellular Localization |
Endoplasmic reticulum membrane {ECO:0000250}; Single-pass type II membrane protein {ECO:0000250}.
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Disease Associations |
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Tissue Specificity |
Expressed at higher level in brain than in non-nervous tissue. Probably highly expressed in neurons. Expressed in mature neurons of the forebrain and appears to be turned on at late stages of neurogenesis. Expressed during late neuronal development in the forebrain. {ECO:0000269PubMed:9813063}.
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.
They are also associated with 8 interaction(s) predicted by orthology.
Experimentally validated |
Total |
3
[view]
|
Protein-Protein |
3
[view]
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Protein-DNA |
0
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Protein-RNA |
0
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DNA-DNA |
0
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RNA-RNA |
0
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DNA-RNA |
0
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Predicted by orthology |
Total |
8 [view]
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|
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Molecular Function |
Accession |
GO Term |
GO:0003824
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catalytic activity
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GO:0004630
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phospholipase D activity
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GO:0070290
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N-acylphosphatidylethanolamine-specific phospholipase D activity
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Biological Process |
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Cellular Component |
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PDB ID |
MGI:1333782
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InterPro |
IPR001736
Phospholipase D/Transphosphatidylase
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PFAM |
PF00614
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PRINTS |
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PIRSF |
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SMART |
SM00155
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TIGRFAMs |
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Modification |
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SwissProt |
O35405
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PhosphoSite |
PhosphoSite-O35405
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TrEMBL |
Q9CW68
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UniProt Splice Variant |
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Entrez Gene |
18807
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UniGene |
Mm.6483
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RefSeq |
XP_006539706
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MGI ID |
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MGI Symbol |
Pld3
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OMIM |
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CCDS |
CCDS21025
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HPRD |
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IMGT |
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EMBL |
AC158304
AF026124
AK003045
AK153508
BC076586
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GenPept |
AAC73069
AAH76586
BAB22530
BAE32053
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