Version 5.4
Mus musculus Protein: Ros1
Summary
InnateDB Protein IDBP-401349.4
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Ros1
Protein Name Ros1 proto-oncogene
Synonyms c-ros; Ros-1;
Species Mus musculus
Ensembl Protein ENSMUSP00000112873
InnateDB Gene IDBG-150588 (Ros1)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 5 experimentally validated interaction(s) in this database.
They are also associated with 6 interaction(s) predicted by orthology.
Experimentally validated
Total 5 [view]
Protein-Protein 4 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 6 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004672 protein kinase activity
GO:0004713 protein tyrosine kinase activity
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0016772 transferase activity, transferring phosphorus-containing groups
Biological Process
GO:0006468 protein phosphorylation
GO:0007283 spermatogenesis
GO:0010629 negative regulation of gene expression
GO:0010966 regulation of phosphate transport
GO:0018108 peptidyl-tyrosine phosphorylation
Cellular Component
GO:0016021 integral component of membrane
Protein Structure and Domains
PDB ID MGI:97999
InterPro IPR000033 LDLR class B repeat
IPR000719 Protein kinase domain
IPR001245 Serine-threonine/tyrosine-protein kinase catalytic domain
IPR002290 Serine/threonine- /dual specificity protein kinase, catalytic domain
IPR003961 Fibronectin, type III
IPR011009 Protein kinase-like domain
IPR020635 Tyrosine-protein kinase, catalytic domain
PFAM PF00058
PF00069
PF07714
PF00041
PF01108
PRINTS PR00109
PIRSF
SMART SM00135
SM00220
SM00060
SM00219
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL E9PWG5
UniProt Splice Variant
Entrez Gene 19886
UniGene Mm.236163
RefSeq
MGI ID
MGI Symbol Ros1
OMIM
CCDS
HPRD
IMGT
EMBL AC153950 AC155831
GenPept

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca