Version 5.4
Mus musculus Protein: Grm4
Summary
InnateDB Protein IDBP-401357.4
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Grm4
Protein Name glutamate receptor, metabotropic 4
Synonyms
Species Mus musculus
Ensembl Protein ENSMUSP00000113819
InnateDB Gene IDBG-156726 (Grm4)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0001642 group III metabotropic glutamate receptor activity
GO:0004930 G-protein coupled receptor activity
Biological Process
GO:0007186 G-protein coupled receptor signaling pathway
GO:0007196 adenylate cyclase-inhibiting G-protein coupled glutamate receptor signaling pathway
GO:0007268 synaptic transmission
GO:0007612 learning
GO:0051966 regulation of synaptic transmission, glutamatergic
Cellular Component
GO:0005887 integral component of plasma membrane
GO:0016021 integral component of membrane
GO:0042734 presynaptic membrane
Protein Structure and Domains
PDB ID MGI:1351341
InterPro IPR000162 GPCR, family 3, metabotropic glutamate receptor
IPR000337 GPCR, family 3
IPR001786 GPCR, family 3, metabotropic glutamate receptor 4
IPR001828 Extracellular ligand-binding receptor
IPR002455 GPCR, family 3, gamma-aminobutyric acid receptor, type B
IPR011500 GPCR, family 3, nine cysteines domain
IPR016196 Major facilitator superfamily domain, general substrate transporter
IPR017978 GPCR, family 3, C-terminal
IPR028082 Periplasmic binding protein-like I
PFAM PF01094
PF07562
PF00003
PRINTS PR00593
PR00248
PR01054
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL G3XA00
UniProt Splice Variant
Entrez Gene 268934
UniGene Mm.489087
RefSeq NP_001277974
MGI ID
MGI Symbol Grm4
OMIM
CCDS CCDS70775
HPRD
IMGT
EMBL AC127341 CH466606
GenPept EDL22539

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca