Version 5.4
Mus musculus Protein: Clcn2
Summary
InnateDB Protein IDBP-401446.4
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Clcn2
Protein Name chloride channel 2
Synonyms AL118368; ClC-2; Clc2; nmf240;
Species Mus musculus
Ensembl Protein ENSMUSP00000112759
InnateDB Gene IDBG-146154 (Clcn2)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.
Predicted by orthology
Total 3 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005216 ion channel activity
GO:0005247 voltage-gated chloride channel activity
GO:0030554 adenyl nucleotide binding
Biological Process
GO:0006821 chloride transport
GO:0034220 ion transmembrane transport
GO:0044070 regulation of anion transport
GO:0055085 transmembrane transport
GO:0060041 retina development in camera-type eye
GO:0060689 cell differentiation involved in salivary gland development
Cellular Component
GO:0016020 membrane
GO:0016021 integral component of membrane
Protein Structure and Domains
PDB ID MGI:105061
InterPro IPR000644 CBS domain
IPR001807 Chloride channel, voltage gated
IPR002244 Chloride channel ClC-2
IPR014743 Chloride channel, core
PFAM PF00571
PF00654
PRINTS PR00762
PR01113
PIRSF
SMART SM00116
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL A9C437
UniProt Splice Variant
Entrez Gene 12724
UniGene Mm.177761
RefSeq
MGI ID
MGI Symbol Clcn2
OMIM
CCDS
HPRD
IMGT
EMBL AC087898 CT010490
GenPept

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca