InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Nt5c1b

Summary

InnateDB Protein

IDBP-401774.4

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Nt5c1b

Protein Name

5'-nucleotidase, cytosolic IB

Synonyms

4921514H13Rik; AIRP; CN-IB;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000112694

InnateDB Gene

IDBG-128655 (Nt5c1b)

Protein Structure

UniProt Annotation

Function

Dephosphorylates the 5' and 2'(3')-phosphates of deoxyribonucleotides. Helps to regulate adenosine levels. {ECO:0000269PubMed:11690631}.

Subcellular Localization

Cytoplasm.

Disease Associations

Tissue Specificity

Highly expressed in testis and brain. Detected at lower levels in skeletal muscle, heart and kidney. {ECO:0000269PubMed:11690631}.

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.

Predicted by orthology
Total	1 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0000166	nucleotide binding
GO:0000287	magnesium ion binding
GO:0008253	5'-nucleotidase activity

Biological Process

GO:0009116	nucleoside metabolic process
GO:0009117	nucleotide metabolic process
GO:0016311	dephosphorylation
GO:0046085	adenosine metabolic process

Cellular Component

GO:0005737	cytoplasm
GO:0005829	cytosol

Protein Structure and Domains

PDB ID

MGI:1918131

InterPro

IPR010394 5-nucleotidase

PFAM

PF06189

PRINTS

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

Q91YE9

PhosphoSite

PhosphoSite-Q91YE9

TrEMBL

Q6P906

UniProt Splice Variant

Entrez Gene

70881

UniGene

Mm.272843

RefSeq

XP_006515271

MGI ID

MGI Symbol

Nt5c1b

OMIM

CCDS

HPRD

IMGT

EMBL

AC157570 AF356186 AJ295253 BC060976

GenPept

AAH60976 AAK39109 CAC44364