Version 5.4
Homo sapiens Protein: AKAP17A
Summary
InnateDB Protein IDBP-40265.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol AKAP17A
Protein Name A kinase (PRKA) anchor protein 17A
Synonyms 721P; AKAP-17A; CCDC133; CXYorf3; DXYS155E; PRKA17A; SFRS17A; XE7; XE7Y;
Species Homo sapiens
Ensembl Protein ENSP00000370660
InnateDB Gene IDBG-40259 (AKAP17A)
Protein Structure
UniProt Annotation
Function Splice factor regulating alternative splice site selection for certain mRNA precursors. Mediates regulation of pre- mRNA splicing in a PKA-dependent manner. {ECO:0000269PubMed:16982639, ECO:0000269PubMed:19840947}.
Subcellular Localization Nucleus speckle {ECO:0000269PubMed:16982639, ECO:0000269PubMed:19840947}.
Disease Associations
Tissue Specificity Widely expressed. Found in heart, brain, lung, liver, skeletal muscle, kidney and pancreas. Expressed in activated B-cells and placenta. Expressed in all cell lines tested including Jurkat-TAg, U-937 and HEK293 cells. {ECO:0000269PubMed:19840947}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 12 experimentally validated interaction(s) in this database.
Experimentally validated
Total 12 [view]
Protein-Protein 12 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0000166 nucleotide binding
Biological Process
Cellular Component
Protein Structure and Domains
PDB ID
InterPro
PFAM
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-Q02040
TrEMBL X6RAJ1
UniProt Splice Variant
Entrez Gene 8227
UniGene Hs.522572
RefSeq
HUGO HGNC:18783
OMIM 465000
CCDS
HPRD 02419
IMGT
EMBL AL683807 CH471074
GenPept EAW98688

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca