Version 5.4
Homo sapiens Gene: AKAP17A
Summary
InnateDB Gene IDBG-40259.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol AKAP17A
Gene Name A kinase (PRKA) anchor protein 17A
Synonyms 721P; AKAP-17A; CCDC133; CXYorf3; DXYS155E; PRKA17A; SFRS17A; XE7; XE7Y
Species Homo sapiens
Ensembl Gene ENSG00000197976
Encoded Proteins
IDBP-40261
A kinase (PRKA) anchor protein 17A
IDBP-40265
A kinase (PRKA) anchor protein 17A
IDBP-597160
A kinase (PRKA) anchor protein 17A
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This locus encodes a protein kinase A anchoring protein. The encoded protein is part of the spliceosome complex and is involved in the regulation of alternate splicing in some mRNA precursors. Alternatively spliced transcript variants have been identified for this gene.[provided by RefSeq, Sep 2010]
Gene Information
Type Protein coding
Genomic Location Chromosome X:1591593-1602514
Strand Forward strand
Band p22.33
Transcripts
ENST00000313871 ENSP00000324827
ENST00000381261 ENSP00000370660
ENST00000474361 ENSP00000435479
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 12 experimentally validated interaction(s) in this database.
Experimentally validated
Total 12 [view]
Protein-Protein 12 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0000166 nucleotide binding
GO:0005515 protein binding
GO:0044822 poly(A) RNA binding
GO:0051018 protein kinase A binding
Biological Process
GO:0006355 regulation of transcription, DNA-templated
GO:0006397 mRNA processing
GO:0007165 signal transduction
GO:0008380 RNA splicing
GO:0042113 B cell activation
GO:0043484 regulation of RNA splicing
Cellular Component
GO:0005634 nucleus
GO:0005681 spliceosomal complex
GO:0016607 nuclear speck
Orthologs
No orthologs found for this gene
Cross-References
SwissProt Q02040
TrEMBL
UniProt Splice Variant
Entrez Gene 8227
UniGene Hs.522572
RefSeq NM_005088
HUGO HGNC:18783
OMIM 312095 465000
CCDS CCDS14116
HPRD 02419
IMGT
EMBL AL683807 BC028151 BC110496 BC110497 L03426 M99578
GenPept AAA36187 AAA61303 AAA61304 AAH28151 AAI10497 AAI10498 CAI41499 CAI41501
RNA Seq Atlas 8227

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca