Homo sapiens Protein: SIRPB1
Summary
InnateDB Protein IDBP-40353.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol SIRPB1
Protein Name signal-regulatory protein beta 1
Synonyms CD172b; SIRP-BETA-1;
Species Homo sapiens
Ensembl Protein ENSP00000279477
InnateDB Gene IDBG-40341 (SIRPB1)
Protein Structure
UniProt Annotation
Function Immunoglobulin-like cell surface receptor involved in the negative regulation of receptor tyrosine kinase-coupled signaling processes. {ECO:0000250}.
Subcellular Localization Membrane; Single-pass type I membrane protein.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 4 experimentally validated interaction(s) in this database.
Experimentally validated
Total 4 [view]
Protein-Protein 4 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
Cellular Component
GO:0016021 integral component of membrane
Protein Structure and Domains
PDB ID
InterPro IPR003596 Immunoglobulin V-set, subgroup
IPR003597 Immunoglobulin C1-set
IPR003599 Immunoglobulin subtype
IPR007110 Immunoglobulin-like domain
IPR013098 Immunoglobulin I-set
IPR013106 Immunoglobulin V-set domain
IPR013151 Immunoglobulin
IPR013162 CD80-like, immunoglobulin C2-set
PFAM PF07654
PF07679
PF07686
PF00047
PF08205
PRINTS
PIRSF
SMART SM00406
SM00407
SM00409
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q5TFQ8
PhosphoSite PhosphoSite-
TrEMBL H3BU43
UniProt Splice Variant
Entrez Gene 10326
UniGene
RefSeq NP_001129316
HUGO HGNC:15928
OMIM 603889
CCDS CCDS46571
HPRD 04866
IMGT
EMBL AK289866 AL049634 AL138804 AL592544 BX537992
GenPept BAF82555 CAD97951 CAI21700 CAI21866