InnateDB Protein
|
IDBP-40619.6
|
Last Modified
|
2014-10-13 [Report errors or provide feedback]
|
Gene Symbol
|
ZBED1
|
Protein Name
|
zinc finger, BED-type containing 1
|
Synonyms
|
ALTE; DREF; hDREF; TRAMP;
|
Species
|
Homo sapiens
|
Ensembl Protein
|
ENSP00000370620
|
InnateDB Gene
|
IDBG-232096 (ZBED1)
|
Protein Structure
|
|
Function |
Binds to 5'-TGTCG[CT]GA[CT]A-3' DNA elements found in the promoter regions of a number of genes related to cell proliferation. Binds to the histone H1 promoter and stimulates transcription. Was first identified as gene weakly similar to Ac transposable elements, but does not code for any transposase activity. {ECO:0000269PubMed:12663651}.
|
Subcellular Localization |
Nucleus {ECO:0000269PubMed:12663651}. Note=In granular structures.
|
Disease Associations |
|
Tissue Specificity |
Ubiquitously expressed at low levels. Expression is highest in skeletal muscle, heart, spleen and placenta.
|
Comments |
|
Number of Interactions
|
This gene and/or its encoded proteins are associated with 40 experimentally validated interaction(s) in this database.
Experimentally validated |
Total |
40
[view]
|
Protein-Protein |
40
[view]
|
Protein-DNA |
0
|
Protein-RNA |
0
|
DNA-DNA |
0
|
RNA-RNA |
0
|
DNA-RNA |
0
|
|
|
|
Molecular Function |
|
Biological Process |
|
Cellular Component |
|
PDB ID |
|
InterPro |
IPR003656
Zinc finger, BED-type
IPR008906
HAT dimerisation domain, C-terminal
IPR012337
Ribonuclease H-like domain
|
PFAM |
PF02892
PF05699
|
PRINTS |
|
PIRSF |
|
SMART |
SM00614
|
TIGRFAMs |
|
Modification |
|
SwissProt |
O96006
|
PhosphoSite |
PhosphoSite-O96006
|
TrEMBL |
C9JXP4
|
UniProt Splice Variant |
|
Entrez Gene |
9189
|
UniGene |
Hs.601629
|
RefSeq |
|
HUGO |
HGNC:447
|
OMIM |
300178
|
CCDS |
CCDS14118
|
HPRD |
02170
|
IMGT |
|
EMBL |
AB018328
AC079176
BC015030
CH471074
Y16947
Y17156
|
GenPept |
AAH15030
BAA34505
CAA76545
CAA76660
EAW98691
EAW98692
|
|
|