InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: RPS3A

Summary

InnateDB Protein

IDBP-41026.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

RPS3A

Protein Name

ribosomal protein S3A

Synonyms

FTE1; MFTL; S3A;

Species

Homo sapiens

Ensembl Protein

ENSP00000346050

InnateDB Gene

IDBG-41024 (RPS3A)

Protein Structure

UniProt Annotation

Function

May play a role during erythropoiesis through regulation of transcription factor DDIT3. {ECO:0000255HAMAP-Rule:MF_03122}.

Subcellular Localization

Cytoplasm {ECO:0000255HAMAP-Rule:MF_03122, ECO:0000269PubMed:17289661}. Nucleus {ECO:0000255HAMAP- Rule:MF_03122}. Note=Localized in cytoplasmic mRNP granules containing untranslated mRNAs.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 182 experimentally validated interaction(s) in this database.
They are also associated with 5 interaction(s) predicted by orthology.

Experimentally validated
Total	182 [view]
Protein-Protein	181 [view]
Protein-DNA	1 [view]
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	5 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003723	RNA binding
GO:0003735	structural constituent of ribosome
GO:0005515	protein binding
GO:0044822	poly(A) RNA binding

Biological Process

GO:0000184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
GO:0002181	cytoplasmic translation
GO:0006412	translation
GO:0006413	translational initiation
GO:0006414	translational elongation
GO:0006415	translational termination
GO:0006614	SRP-dependent cotranslational protein targeting to membrane
GO:0010467	gene expression
GO:0016032	viral process
GO:0016070	RNA metabolic process
GO:0016071	mRNA metabolic process
GO:0019058	viral life cycle
GO:0019083	viral transcription
GO:0030154	cell differentiation
GO:0043066	negative regulation of apoptotic process
GO:0044267	cellular protein metabolic process

Cellular Component

GO:0005622	intracellular
GO:0005634	nucleus
GO:0005730	nucleolus
GO:0005737	cytoplasm
GO:0005829	cytosol
GO:0005840	ribosome
GO:0022627	cytosolic small ribosomal subunit
GO:0030529	ribonucleoprotein complex
GO:0070062	extracellular vesicular exosome