InnateDB Protein
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IDBP-41569.7
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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HPR
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Protein Name
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haptoglobin
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Synonyms
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A-259H10.2; HP;
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Species
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Homo sapiens
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Ensembl Protein
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ENSP00000228226
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InnateDB Gene
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IDBG-720810 (HPR)
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Protein Structure
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Function |
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Subcellular Localization |
Secreted {ECO:0000305}.
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Disease Associations |
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Tissue Specificity |
In adult liver the amount of HPR mRNA is at the lower limit of detection, therefore the extent of its expression is at most less than 1000-fold that of the HP1F gene. No HPR mRNA can be detected in fetal liver. Expressed in Hep-G2 and leukemia MOLT-4 cell lines. {ECO:0000269PubMed:8945641}.
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated |
Total |
2
[view]
|
Protein-Protein |
2
[view]
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Protein-DNA |
0
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Protein-RNA |
0
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DNA-DNA |
0
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RNA-RNA |
0
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DNA-RNA |
0
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Predicted by orthology |
Total |
1 [view]
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Molecular Function |
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Biological Process |
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Cellular Component |
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PDB ID |
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InterPro |
IPR001254
Peptidase S1
IPR001314
Peptidase S1A, chymotrypsin-type
IPR009003
Trypsin-like cysteine/serine peptidase domain
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PFAM |
PF00089
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PRINTS |
PR00722
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PIRSF |
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SMART |
SM00020
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TIGRFAMs |
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Modification |
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SwissProt |
P00739
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PhosphoSite |
PhosphoSite-P00739
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TrEMBL |
Q6PEJ8
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UniProt Splice Variant |
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Entrez Gene |
3250
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UniGene |
Hs.655361
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RefSeq |
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HUGO |
HGNC:5141
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OMIM |
140210
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CCDS |
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HPRD |
00773
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IMGT |
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EMBL |
AC004682
AC009087
BC017862
BC058031
K03431
M10935
M69197
X01787
X01788
X01790
X01792
X01794
X89214
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GenPept |
AAA88079
AAA88081
AAC27433
AAH17862
AAH58031
CAA25927
CAA61501
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