InnateDB Protein
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IDBP-42642.6
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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CEBPG
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Protein Name
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CCAAT/enhancer binding protein (C/EBP), gamma
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Synonyms
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GPE1BP; IG/EBP-1;
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Species
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Homo sapiens
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Ensembl Protein
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ENSP00000284000
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InnateDB Gene
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IDBG-42640 (CEBPG)
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Protein Structure
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Function |
Transcription factor that binds to the enhancer element PRE-I (positive regulatory element-I) of the IL-4 gene. Might change the DNA-binding specificity of other transcription factors and recruit them to unusual DNA sites.
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Subcellular Localization |
Nucleus.
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Disease Associations |
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Tissue Specificity |
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 38 experimentally validated interaction(s) in this database.
They are also associated with 10 interaction(s) predicted by orthology.
Experimentally validated |
Total |
38
[view]
|
Protein-Protein |
35
[view]
|
Protein-DNA |
3
[view]
|
Protein-RNA |
0
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DNA-DNA |
0
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RNA-RNA |
0
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DNA-RNA |
0
|
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Predicted by orthology |
Total |
10 [view]
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|
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Molecular Function |
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Biological Process |
GO:0001889
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liver development
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GO:0006351
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transcription, DNA-templated
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GO:0006355
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regulation of transcription, DNA-templated
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GO:0006357
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regulation of transcription from RNA polymerase II promoter
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GO:0006955
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immune response
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GO:0016071
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mRNA metabolic process
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GO:0030183
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B cell differentiation
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GO:0042267
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natural killer cell mediated cytotoxicity
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GO:0043353
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enucleate erythrocyte differentiation
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GO:0043388
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positive regulation of DNA binding
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GO:0043433
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negative regulation of sequence-specific DNA binding transcription factor activity
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GO:0045078
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positive regulation of interferon-gamma biosynthetic process
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GO:0045739
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positive regulation of DNA repair
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GO:0051091
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positive regulation of sequence-specific DNA binding transcription factor activity
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Cellular Component |
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PDB ID |
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InterPro |
IPR004827
Basic-leucine zipper domain
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PFAM |
PF00170
PF07716
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PRINTS |
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PIRSF |
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SMART |
SM00338
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TIGRFAMs |
|
Modification |
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SwissProt |
P53567
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PhosphoSite |
PhosphoSite-P53567
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TrEMBL |
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UniProt Splice Variant |
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Entrez Gene |
1054
|
UniGene |
Hs.732150
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RefSeq |
NP_001797
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HUGO |
HGNC:1837
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OMIM |
138972
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CCDS |
CCDS12432
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HPRD |
00738
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IMGT |
|
EMBL |
AK313634
BC007582
BC013128
BT019819
BT019820
U20240
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GenPept |
AAC50201
AAH07582
AAH13128
AAV38622
AAV38623
BAG36393
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