Version 5.4
| Homo sapiens Protein: PKD1L2 | |||||||
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| Summary | |||||||
| InnateDB Protein | IDBP-43484.6 | ||||||
| Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||
| Gene Symbol | PKD1L2 | ||||||
| Protein Name | polycystic kidney disease 1-like 2 | ||||||
| Synonyms | |||||||
| Species | Homo sapiens | ||||||
| Ensembl Protein | ENSP00000337397 | ||||||
| InnateDB Gene | IDBG-43476 (PKD1L2) | ||||||
| Protein Structure |
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| UniProt Annotation | |||||||
| Function | May function as an ion-channel regulator. May function as a G-protein-coupled receptor. {ECO:0000269PubMed:15203210}. | ||||||
| Subcellular Localization | Membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}. | ||||||
| Disease Associations | |||||||
| Tissue Specificity | Expressed in all tissues tested including brain, placenta, mammary gland, testis, lung and liver. Highest expression in skeletal muscle. Isoform 2 is expressed in heart and kidney. {ECO:0000269PubMed:12782129}. | ||||||
| Comments | |||||||
| Interactions | |||||||
| Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
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| Gene Ontology | |||||||
Molecular Function |
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| Biological Process |
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| Cellular Component |
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| Protein Structure and Domains | |||||||
| PDB ID | |||||||
| InterPro |
IPR000601
PKD domain IPR000922 D-galactoside/L-rhamnose binding SUEL lectin domain IPR001304 C-type lectin IPR002859 PKD/REJ-like protein IPR013041 Coatomer/clathrin adaptor appendage, Ig-like subdomain IPR014010 Egg jelly receptor, REJ-like IPR016187 C-type lectin fold |
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| PFAM |
PF00801
PF02140 PF00059 PF02010 |
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| PRINTS | |||||||
| PIRSF | |||||||
| SMART |
SM00034
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| TIGRFAMs | |||||||
| Post-translational Modifications | |||||||
| Modification | |||||||
| Cross-References | |||||||
| SwissProt | Q7Z442 | ||||||
| PhosphoSite | PhosphoSite-Q7Z442 | ||||||
| TrEMBL | Q6AI51 | ||||||
| UniProt Splice Variant | |||||||
| Entrez Gene | 114780 | ||||||
| UniGene | Hs.737982 | ||||||
| RefSeq | NP_001070248 | ||||||
| HUGO | HGNC:21715 | ||||||
| OMIM | 607894 | ||||||
| CCDS | |||||||
| HPRD | 06990 | ||||||
| IMGT | |||||||
| EMBL | AB067466 AC092718 AC131888 AK098052 AK127266 AK131378 AY164483 AY371495 BC004562 BC014157 CR627341 | ||||||
| GenPept | AAH04562 AAH14157 AAO32796 AAQ73173 BAB67772 BAC05222 BAC86906 BAD18529 CAH10372 | ||||||