Version 5.4
Homo sapiens Protein: FEZ2
Summary
InnateDB Protein IDBP-44303.7
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol FEZ2
Protein Name fasciculation and elongation protein zeta 2 (zygin II)
Synonyms HUM3CL;
Species Homo sapiens
Ensembl Protein ENSP00000368547
InnateDB Gene IDBG-44299 (FEZ2)
Protein Structure
UniProt Annotation
Function Involved in axonal outgrowth and fasciculation. {ECO:0000250}.
Subcellular Localization
Disease Associations
Tissue Specificity Expressed in nonneural tissues, such as heart, lung, spleen, muscle, testis, placenta and melanocytes.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 21 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 21 [view]
Protein-Protein 21 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
GO:0007165 signal transduction
GO:0007399 nervous system development
GO:0007411 axon guidance
Cellular Component
Protein Structure and Domains
PDB ID
InterPro IPR011680 Fasciculation and elongation protein zeta, FEZ
PFAM PF07763
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q9UHY8
PhosphoSite PhosphoSite-Q9UHY8
TrEMBL Q6P2J5
UniProt Splice Variant
Entrez Gene 9637
UniGene Hs.258563
RefSeq NP_001036013
HUGO HGNC:3660
OMIM 604826
CCDS CCDS46258
HPRD 09213
IMGT
EMBL AB076184 AC007363 AC007401 AF113124 BC064484 BC089390 U60061 U69140
GenPept AAB40661 AAC51283 AAF14865 AAH64484 AAH89390 AAY14650 BAD06207

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca