Homo sapiens Protein: WIF1
Summary
InnateDB Protein IDBP-45234.5
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol WIF1
Protein Name WNT inhibitory factor 1
Synonyms WIF-1;
Species Homo sapiens
Ensembl Protein ENSP00000286574
InnateDB Gene IDBG-45232 (WIF1)
Protein Structure
UniProt Annotation
Function Binds to WNT proteins and inhibits their activities. May be involved in mesoderm segmentation.
Subcellular Localization Secreted.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 11 experimentally validated interaction(s) in this database.
Experimentally validated
Total 11 [view]
Protein-Protein 11 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
GO:0007165 signal transduction
GO:0007275 multicellular organismal development
GO:0016055 Wnt signaling pathway
GO:0045600 positive regulation of fat cell differentiation
Cellular Component
GO:0005576 extracellular region
Protein Structure and Domains
PDB ID
InterPro IPR000742 Epidermal growth factor-like domain
IPR003306 WIF domain
IPR013111 EGF-like domain, extracellular
IPR013309 Wnt inhibitory factor (WIF)-1
PFAM PF00008
PF02019
PF07974
PRINTS PR01901
PIRSF
SMART SM00181
SM00469
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q9Y5W5
PhosphoSite PhosphoSite-Q9Y5W5
TrEMBL F5H8A3
UniProt Splice Variant
Entrez Gene 11197
UniGene Hs.284122
RefSeq NP_009122
HUGO HGNC:18081
OMIM 605186
CCDS CCDS8971
HPRD 05541
IMGT
EMBL AC026124 AC135895 AF122922 AK301818 AY358344 BC018037
GenPept AAD25402 AAH18037 AAQ88710 BAG63265