Version 5.4
Homo sapiens Protein: INSL6
Summary
InnateDB Protein IDBP-47237.4
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol INSL6
Protein Name insulin-like 6
Synonyms RIF1;
Species Homo sapiens
Ensembl Protein ENSP00000371054
InnateDB Gene IDBG-47235 (INSL6)
Protein Structure
UniProt Annotation
Function May have a role in sperm development and fertilization.
Subcellular Localization Secreted {ECO:0000250}.
Disease Associations
Tissue Specificity Testis specific.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0005179 hormone activity
Biological Process
GO:0007283 spermatogenesis
GO:0007286 spermatid development
GO:0008150 biological_process
GO:0008584 male gonad development
GO:0009566 fertilization
GO:0030317 sperm motility
GO:0043066 negative regulation of apoptotic process
Cellular Component
GO:0005575 cellular_component
GO:0005576 extracellular region
Protein Structure and Domains
PDB ID
InterPro IPR016179 Insulin-like
IPR017100 Insulin-like peptide 6
PFAM PF00049
PRINTS
PIRSF PIRSF037062
SMART SM00078
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q9Y581
PhosphoSite PhosphoSite-
TrEMBL
UniProt Splice Variant
Entrez Gene 11172
UniGene
RefSeq NP_009110
HUGO HGNC:6089
OMIM 606414
CCDS CCDS6458
HPRD 08401
IMGT
EMBL AF135824 AF156094 AL161450 BC126473 BC126475
GenPept AAD39003 AAF29604 AAI26474 AAI26476 CAD13336

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca