InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: INSL4

Summary

InnateDB Protein

IDBP-47287.4

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

INSL4

Protein Name

insulin-like 4 (placenta)

Synonyms

EPIL; PLACENTIN;

Species

Homo sapiens

Ensembl Protein

ENSP00000239316

InnateDB Gene

IDBG-47285 (INSL4)

Protein Structure

UniProt Annotation

Function

May play an important role in trophoblast development and in the regulation of bone formation.

Subcellular Localization

Secreted {ECO:0000250}.

Disease Associations

Tissue Specificity

Expressed in placenta, uterus and in fetal perichondrium. Expression levels were increased in both early placentas and molar pregnancies and were reduced in choriocarcinoma cells. {ECO:0000269PubMed:12414911, ECO:0000269PubMed:9740319}.

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005102	receptor binding
GO:0005159	insulin-like growth factor receptor binding
GO:0005179	hormone activity

Biological Process

GO:0007165	signal transduction
GO:0007267	cell-cell signaling
GO:0007275	multicellular organismal development
GO:0007565	female pregnancy
GO:0008283	cell proliferation