InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: SMC4

Summary

InnateDB Protein

IDBP-473453.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

SMC4

Protein Name

structural maintenance of chromosomes 4

Synonyms

CAP-C; CAPC; hCAP-C; SMC-4; SMC4L1;

Species

Homo sapiens

Ensembl Protein

ENSP00000417964

InnateDB Gene

IDBG-63513 (SMC4)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 47 experimentally validated interaction(s) in this database.

Experimentally validated
Total	47 [view]
Protein-Protein	43 [view]
Protein-DNA	4 [view]
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004888	transmembrane signaling receptor activity
GO:0005515	protein binding
GO:0005524	ATP binding

Biological Process

GO:0006935	chemotaxis
GO:0007165	signal transduction
GO:0051276	chromosome organization

Cellular Component

GO:0005634	nucleus
GO:0005694	chromosome
GO:0005737	cytoplasm
GO:0016020	membrane

Protein Structure and Domains

PDB ID

InterPro

IPR003122 Chemotaxis methyl-accepting receptor, ligand-binding
IPR003395 RecF/RecN/SMC, N-terminal
IPR009053 Prefoldin
IPR010935 SMCs flexible hinge
IPR027417 P-loop containing nucleoside triphosphate hydrolase

PFAM

PF02203
PF02463
PF06470

PRINTS

PIRSF

SMART

SM00319
SM00968

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite

PhosphoSite-

TrEMBL

E9PD53

UniProt Splice Variant

Entrez Gene

10051

UniGene

Hs.58992

RefSeq

NP_001275682

HUGO

HGNC:14013

OMIM

605575

CCDS

CCDS75046

HPRD

09276

IMGT

EMBL

AC024221

GenPept