InnateDB Protein
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IDBP-473981.3
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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GCLC
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Protein Name
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glutamate-cysteine ligase, catalytic subunit
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Synonyms
|
GCL; GCS; GLCL; GLCLC;
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Species
|
Homo sapiens
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Ensembl Protein
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ENSP00000426578
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InnateDB Gene
|
IDBG-91041 (GCLC)
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Protein Structure
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|
Function |
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Subcellular Localization |
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Disease Associations |
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Tissue Specificity |
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 15 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated |
Total |
15
[view]
|
Protein-Protein |
7
[view]
|
Protein-DNA |
7
[view]
|
Protein-RNA |
1
[view]
|
DNA-DNA |
0
|
RNA-RNA |
0
|
DNA-RNA |
0
|
|
Predicted by orthology |
Total |
1 [view]
|
|
|
Molecular Function |
Accession |
GO Term |
GO:0004357
|
glutamate-cysteine ligase activity
|
|
Biological Process |
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Cellular Component |
|
PDB ID |
|
InterPro |
IPR004308
Glutamate-cysteine ligase catalytic subunit
|
PFAM |
PF03074
|
PRINTS |
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PIRSF |
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SMART |
|
TIGRFAMs |
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Modification |
|
SwissProt |
|
PhosphoSite |
PhosphoSite-
|
TrEMBL |
H0YAB6
|
UniProt Splice Variant |
|
Entrez Gene |
2729
|
UniGene |
Hs.654465
|
RefSeq |
|
HUGO |
HGNC:4311
|
OMIM |
606857
|
CCDS |
|
HPRD |
06032
|
IMGT |
|
EMBL |
AL033397
|
GenPept |
|
|
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