Version 5.4
Homo sapiens Protein: XRN1
Summary
InnateDB Protein IDBP-474100.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol XRN1
Protein Name 5'-3' exoribonuclease 1
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000420786
InnateDB Gene IDBG-59457 (XRN1)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 74 experimentally validated interaction(s) in this database.
Experimentally validated
Total 74 [view]
Protein-Protein 74 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0003676 nucleic acid binding
GO:0004527 exonuclease activity
Biological Process
GO:0090305 nucleic acid phosphodiester bond hydrolysis
Cellular Component
GO:0005622 intracellular
Protein Structure and Domains
PDB ID
InterPro IPR004859 Putative 5-3 exonuclease
PFAM PF03159
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL F8WDA0
UniProt Splice Variant
Entrez Gene 54464
UniGene Hs.629790
RefSeq
HUGO HGNC:30654
OMIM 607994
CCDS
HPRD 10470
IMGT
EMBL AC023508 AC109992
GenPept

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca