Version 5.4
Homo sapiens Protein: IMPDH1
Summary
InnateDB Protein IDBP-474369.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol IMPDH1
Protein Name IMP (inosine 5'-monophosphate) dehydrogenase 1
Synonyms IMPD; IMPD1; LCA11; RP10; sWSS2608;
Species Homo sapiens
Ensembl Protein ENSP00000418742
InnateDB Gene IDBG-39659 (IMPDH1)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 8 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 8 [view]
Protein-Protein 8 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003824 catalytic activity
GO:0030554 adenyl nucleotide binding
Biological Process
GO:0055114 oxidation-reduction process
Cellular Component
Protein Structure and Domains
PDB ID
InterPro IPR000644 CBS domain
IPR001093 IMP dehydrogenase/GMP reductase
PFAM PF00571
PF00478
PRINTS
PIRSF
SMART SM00116
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL H7C511
UniProt Splice Variant
Entrez Gene 3614
UniGene Hs.654401
RefSeq XP_006716033
HUGO HGNC:6052
OMIM 146690
CCDS
HPRD 08853
IMGT
EMBL AC010655
GenPept

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca