InnateDB Protein
|
IDBP-475399.4
|
Last Modified
|
2014-10-13 [Report errors or provide feedback]
|
Gene Symbol
|
ARSI
|
Protein Name
|
arylsulfatase family, member I
|
Synonyms
|
|
Species
|
Homo sapiens
|
Ensembl Protein
|
ENSP00000426879
|
InnateDB Gene
|
IDBG-53501 (ARSI)
|
Protein Structure
|
|
Function |
Displays arylsulfatase activity at neutral pH, when co- expressed with SUMF1; arylsulfatase activity is measured in the secretion medium of retinal cell line, but no activity is recorded when measured in cell extracts. {ECO:0000269PubMed:16500042, ECO:0000269PubMed:19262745}.
|
Subcellular Localization |
Secreted {ECO:0000269PubMed:19262745}. Endoplasmic reticulum {ECO:0000269PubMed:19262745}. Note=Localized in the intracellular granular structures.
|
Disease Associations |
|
Tissue Specificity |
Expressed in placenta, in embryonic stem cells, fetal eyes and lens. {ECO:0000269PubMed:16500042, ECO:0000269PubMed:19262745}.
|
Comments |
|
Number of Interactions
|
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
|
Molecular Function |
|
Biological Process |
|
Cellular Component |
|
PDB ID |
|
InterPro |
IPR000917
Sulfatase
IPR017850
Alkaline-phosphatase-like, core domain
|
PFAM |
PF00884
|
PRINTS |
|
PIRSF |
|
SMART |
|
TIGRFAMs |
|
Modification |
|
SwissProt |
Q5FYB1
|
PhosphoSite |
PhosphoSite-Q5FYB1
|
TrEMBL |
D6RDH0
|
UniProt Splice Variant |
|
Entrez Gene |
340075
|
UniGene |
Hs.591252
|
RefSeq |
|
HUGO |
HGNC:32521
|
OMIM |
610009
|
CCDS |
|
HPRD |
16510
|
IMGT |
|
EMBL |
AB448735
AC011372
AK122641
AY875937
BC129995
BC129996
|
GenPept |
AAI29996
AAI29997
AAW66665
BAG53634
BAH11166
|
|
|