Version 5.4
Homo sapiens Protein: APTX
Summary
InnateDB Protein IDBP-475429.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol APTX
Protein Name aprataxin
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000417649
InnateDB Gene IDBG-56157 (APTX)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 26 experimentally validated interaction(s) in this database.
Experimentally validated
Total 26 [view]
Protein-Protein 26 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0003677 DNA binding
GO:0003824 catalytic activity
GO:0005515 protein binding
GO:0033699 DNA 5'-adenosine monophosphate hydrolase activity
Biological Process
GO:0000738 DNA catabolic process, exonucleolytic
GO:0006281 DNA repair
Cellular Component
GO:0005634 nucleus
GO:0005730 nucleolus
Protein Structure and Domains
PDB ID
InterPro IPR008984 SMAD/FHA domain
IPR011146 HIT-like domain
PFAM
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL C9J8U3
UniProt Splice Variant
Entrez Gene 54840
UniGene Hs.734329
RefSeq
HUGO HGNC:15984
OMIM 606350
CCDS
HPRD 05892
IMGT
EMBL AL162590 AL353717
GenPept

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca