InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: TRIM34

Summary

InnateDB Protein

IDBP-475656.4

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

TRIM34

Protein Name

tripartite motif containing 34

Synonyms

Species

Homo sapiens

Ensembl Protein

ENSP00000422947

InnateDB Gene

IDBG-547400 (TRIM34)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Isoform 1 is the most abundant form. It is highly expressed in the placenta, spleen, colon and peripheral blood leukocytes. {ECO:0000269PubMed:11013086}.

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 10 experimentally validated interaction(s) in this database.

Experimentally validated
Total	10 [view]
Protein-Protein	9 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	1 [view]
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003674	molecular_function
GO:0005515	protein binding
GO:0008270	zinc ion binding
GO:0046872	metal ion binding

Biological Process

GO:0051091	positive regulation of sequence-specific DNA binding transcription factor activity
GO:0070206	protein trimerization

Cellular Component

GO:0005622	intracellular
GO:0005737	cytoplasm

Protein Structure and Domains

PDB ID

InterPro

IPR000315 Zinc finger, B-box
IPR001841 Zinc finger, RING-type
IPR001870 B30.2/SPRY domain
IPR003877 SPRY domain
IPR003879 Butyrophylin-like
IPR008985 Concanavalin A-like lectin/glucanases superfamily
IPR018957 Zinc finger, C3HC4 RING-type

PFAM

PF00643
PF13639
PF14634
PF00622
PF00097

PRINTS

PR01407

PIRSF

SMART

SM00336
SM00184
SM00449

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt