Version 5.4
Homo sapiens Protein: GPBP1
Summary
InnateDB Protein IDBP-475892.4
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol GPBP1
Protein Name GC-rich promoter binding protein 1
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000421709
InnateDB Gene IDBG-22387 (GPBP1)
Protein Structure
UniProt Annotation
Function Functions as a GC-rich promoter-specific transactivating transcription factor. {ECO:0000250}.
Subcellular Localization Nucleus. Cytoplasm. Note=According to PubMed:12842993, it localizes to the cytoplasm.
Disease Associations
Tissue Specificity Widely expressed. Some isoforms may be specifically expressed in veins and arteries (at protein level). Isoform 4 is widely expressed. Isoform 1, isoform 2 and isoform 3 may be specifically expressed in vascular smooth muscle cells. {ECO:0000269PubMed:12842993, ECO:0000269PubMed:14612417}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.
They are also associated with 5 interaction(s) predicted by orthology.
Experimentally validated
Total 3 [view]
Protein-Protein 3 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 5 [view]
Gene Ontology

Molecular Function
Accession GO Term
Biological Process
GO:0006351 transcription, DNA-templated
Cellular Component
GO:0005730 nucleolus
GO:0005737 cytoplasm
GO:0005886 plasma membrane
GO:0043231 intracellular membrane-bounded organelle
Protein Structure and Domains
PDB ID
InterPro
PFAM
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q86WP2
PhosphoSite PhosphoSite-Q86WP2
TrEMBL
UniProt Splice Variant
Entrez Gene 65056
UniGene Hs.694984
RefSeq NP_001190175
HUGO HGNC:29520
OMIM 608412
CCDS CCDS56368
HPRD 16333
IMGT
EMBL AC034244 AK024807 AL136844 AL161991 AY226828 BC000267 BC070132 BC113004 CH471123
GenPept AAH00267 AAH70132 AAI13005 AAO34124 BAB15013 CAB66778 CAB82324 EAW54965 EAW54966

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca