InnateDB Protein
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IDBP-476486.4
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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FCRL2
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Protein Name
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Fc receptor-like 2
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Synonyms
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Species
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Homo sapiens
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Ensembl Protein
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ENSP00000417393
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InnateDB Gene
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IDBG-103696 (FCRL2)
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Protein Structure
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Function |
May have an regulatory role in normal and neoplastic B cell development. {ECO:0000269PubMed:11493702}.
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Subcellular Localization |
Cell membrane {ECO:0000269PubMed:16849395}; Single-pass type I membrane protein {ECO:0000269PubMed:16849395}.
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Disease Associations |
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Tissue Specificity |
Expressed in the secondary lymphoid organs, spleen and lymph node. Expression is limited to the mature B-cell lines. Highly expressed in CD19 and within the mantle zones of the tonsil tissue. Isoform 2 is expressed in the spleen, peripheral blood and bone marrow. Isoform 2 and isoform 4 are expressed in B- cell lines. Preferentially expressed in memory B-cells (at protein level). {ECO:0000269PubMed:11162587, ECO:0000269PubMed:11493702, ECO:0000269PubMed:11929751, ECO:0000269PubMed:16849395}.
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
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Molecular Function |
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Biological Process |
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Cellular Component |
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PDB ID |
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InterPro |
IPR007110
Immunoglobulin-like domain
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PFAM |
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PRINTS |
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PIRSF |
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SMART |
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TIGRFAMs |
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Modification |
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SwissProt |
Q96LA5
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PhosphoSite |
PhosphoSite-Q96LA5
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TrEMBL |
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UniProt Splice Variant |
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Entrez Gene |
79368
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UniGene |
Hs.437393
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RefSeq |
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HUGO |
HGNC:14875
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OMIM |
606509
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CCDS |
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HPRD |
07351
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IMGT |
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EMBL |
AF319438
AF319439
AF319440
AF390037
AF459633
AL356276
AY043465
AY358130
BC069185
BC129836
CH471121
EF064733
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GenPept |
AAH69185
AAI29837
AAK01402
AAK01403
AAK01404
AAK91778
AAL60249
AAM12152
AAQ88497
ABK41916
CAH73060
CAH73061
CAH73062
CAH73063
EAW52864
EAW52867
EAW52869
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