InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: PRDM5

Summary

InnateDB Protein

IDBP-476550.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

PRDM5

Protein Name

PR domain containing 5

Synonyms

BCS2; PFM2;

Species

Homo sapiens

Ensembl Protein

ENSP00000422309

InnateDB Gene

IDBG-35974 (PRDM5)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 4 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.

Experimentally validated
Total	4 [view]
Protein-Protein	3 [view]
Protein-DNA	1 [view]
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	1 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0000976	transcription regulatory region sequence-specific DNA binding
GO:0005515	protein binding
GO:0008168	methyltransferase activity
GO:0043565	sequence-specific DNA binding
GO:0044212	transcription regulatory region DNA binding
GO:0046872	metal ion binding
GO:0070491	repressing transcription factor binding

Biological Process

GO:0000278	mitotic cell cycle
GO:0006351	transcription, DNA-templated
GO:0016575	histone deacetylation
GO:0045892	negative regulation of transcription, DNA-templated
GO:0051567	histone H3-K9 methylation

Cellular Component

GO:0005634

nucleus

Protein Structure and Domains

PDB ID

InterPro

IPR001214 SET domain
IPR007087 Zinc finger, C2H2
IPR015880 Zinc finger, C2H2-like
IPR017125 PR-domain zinc finger protein PRDM5
IPR022755 Zinc finger, double-stranded RNA binding

PFAM

PF00856
PF00096
PF12171

PRINTS

PIRSF

PIRSF037162

SMART

SM00317
SM00355

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt