Version 5.4
Homo sapiens Gene: PRDM5
Summary
InnateDB Gene IDBG-35974.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol PRDM5
Gene Name PR domain containing 5
Synonyms BCS2; PFM2
Species Homo sapiens
Ensembl Gene ENSG00000138738
Encoded Proteins
IDBP-35976
PR domain containing 5
IDBP-241594
PR domain containing 5
IDBP-376797
PR domain containing 5
IDBP-476550
PR domain containing 5
IDBP-478068
PR domain containing 5
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary The protein encoded by this gene is a transcription factor of the PR-domain protein family. It contains a PR-domain and multiple zinc finger motifs. Transcription factors of the PR-domain family are known to be involved in cell differentiation and tumorigenesis. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 4:120684919-120922870
Strand Reverse strand
Band q27
Transcripts
ENST00000264808 ENSP00000264808
ENST00000394435 ENSP00000377955
ENST00000428209 ENSP00000404832
ENST00000513741
ENST00000515109 ENSP00000422309
ENST00000505484
ENST00000506065
ENST00000503661
ENST00000502409 ENSP00000424861
ENST00000512845
ENST00000507611
ENST00000505033
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 4 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 4 [view]
Protein-Protein 3 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0000976 transcription regulatory region sequence-specific DNA binding
GO:0005515 protein binding
GO:0008168 methyltransferase activity
GO:0043565 sequence-specific DNA binding
GO:0044212 transcription regulatory region DNA binding
GO:0046872 metal ion binding
GO:0070491 repressing transcription factor binding
Biological Process
GO:0000278 mitotic cell cycle
GO:0006351 transcription, DNA-templated
GO:0016575 histone deacetylation
GO:0045892 negative regulation of transcription, DNA-templated
GO:0051567 histone H3-K9 methylation
Cellular Component
GO:0005634 nucleus
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000029913
View Gene Order
ENSBTAG00000012111
Not yet available
Cross-References
SwissProt Q9NQX1
TrEMBL
UniProt Splice Variant
Entrez Gene 11107
UniGene Hs.630705 Hs.659137 Hs.666782
RefSeq NM_001300824 XM_005262707 NM_001300823 NM_018699 XM_005262706 XM_005262708 XM_006714072
HUGO HGNC:9349
OMIM 614161
CCDS CCDS75187 CCDS3716 CCDS75188
HPRD 17902
IMGT
EMBL AC025741 AC104068 AC104795 AF272897 AK056352 BC066942 BC121037 BC121038
GenPept AAF78077 AAH66942 AAI21038 AAI21039 BAG51686
RNA Seq Atlas 11107

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca