InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: ATP8A1

Summary

InnateDB Protein

IDBP-477524.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

ATP8A1

Protein Name

ATPase, aminophospholipid transporter (APLT), class I, type 8A, member 1

Synonyms

ATPASEII; ATPIA; ATPP2;

Species

Homo sapiens

Ensembl Protein

ENSP00000426495

InnateDB Gene

IDBG-15848 (ATP8A1)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.

Experimentally validated
Total	3 [view]
Protein-Protein	3 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0000287	magnesium ion binding
GO:0004012	phospholipid-translocating ATPase activity
GO:0005524	ATP binding
GO:0019829	cation-transporting ATPase activity

Biological Process

GO:0006812	cation transport
GO:0045332	phospholipid translocation

Cellular Component

GO:0016021

integral component of membrane

Protein Structure and Domains

PDB ID

InterPro

IPR001757 Cation-transporting P-type ATPase
IPR023214 HAD-like domain

PFAM

PF00702
PF08282
PF13419

PRINTS

PR00119
PR00120

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite

PhosphoSite-

TrEMBL

H0YAA1

UniProt Splice Variant

Entrez Gene

10396

UniGene

Hs.435052

RefSeq

HUGO

HGNC:13531

OMIM

609542

CCDS

HPRD

16527

IMGT

EMBL

AC084010 AC096734 AC110788 AC139717

GenPept