Homo sapiens Gene: ATP8A1 | |||||||||||||||||||
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Summary | |||||||||||||||||||
InnateDB Gene | IDBG-15848.6 | ||||||||||||||||||
Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||||||||||||
Gene Symbol | ATP8A1 | ||||||||||||||||||
Gene Name | ATPase, aminophospholipid transporter (APLT), class I, type 8A, member 1 | ||||||||||||||||||
Synonyms | ATPASEII; ATPIA; ATPP2 | ||||||||||||||||||
Species | Homo sapiens | ||||||||||||||||||
Ensembl Gene | ENSG00000124406 | ||||||||||||||||||
Encoded Proteins |
ATPase, aminophospholipid transporter (APLT), class I, type 8A, member 1
ATPase, aminophospholipid transporter (APLT), class I, type 8A, member 1
ATPase, aminophospholipid transporter (APLT), class I, type 8A, member 1
ATPase, aminophospholipid transporter (APLT), class I, type 8A, member 1
ATPase, aminophospholipid transporter (APLT), class I, type 8A, member 1
ATPase, aminophospholipid transporter (APLT), class I, type 8A, member 1
ATPase, aminophospholipid transporter (APLT), class I, type 8A, member 1
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Protein Structure | |||||||||||||||||||
Useful resources | Stemformatics EHFPI ImmGen | ||||||||||||||||||
Entrez Gene | |||||||||||||||||||
Summary |
The P-type adenosinetriphosphatases (P-type ATPases) are a family of proteins which use the free energy of ATP hydrolysis to drive uphill transport of ions across membranes. Several subfamilies of P-type ATPases have been identified. One subfamily catalyzes transport of heavy metal ions. Another subfamily transports non-heavy metal ions (NMHI). The protein encoded by this gene is a member of the third subfamily of P-type ATPases and acts to transport amphipaths, such as phosphatidylserine. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008] |
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Gene Information | |||||||||||||||||||
Type | Protein coding | ||||||||||||||||||
Genomic Location | Chromosome 4:42408373-42657105 | ||||||||||||||||||
Strand | Reverse strand | ||||||||||||||||||
Band | p13 | ||||||||||||||||||
Transcripts | |||||||||||||||||||
Interactions | |||||||||||||||||||
Number of Interactions |
This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.
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Gene Ontology | |||||||||||||||||||
Molecular Function |
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Biological Process |
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Cellular Component |
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Orthologs | |||||||||||||||||||
Species
Mus musculus
Bos taurus
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Gene ID
Gene Order
Not yet available
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Pathways | |||||||||||||||||||
NETPATH | |||||||||||||||||||
REACTOME |
Ion transport by P-type ATPases pathway
Transmembrane transport of small molecules pathway
Ion channel transport pathway
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KEGG | |||||||||||||||||||
INOH | |||||||||||||||||||
PID NCI | |||||||||||||||||||
Cross-References | |||||||||||||||||||
SwissProt | |||||||||||||||||||
TrEMBL | |||||||||||||||||||
UniProt Splice Variant | |||||||||||||||||||
Entrez Gene | |||||||||||||||||||
UniGene | Hs.435052 | ||||||||||||||||||
RefSeq | NM_001105529 NM_006095 XM_005248043 XM_006713989 | ||||||||||||||||||
HUGO | |||||||||||||||||||
OMIM | |||||||||||||||||||
CCDS | CCDS3466 CCDS47049 | ||||||||||||||||||
HPRD | 16527 | ||||||||||||||||||
IMGT | |||||||||||||||||||
EMBL | |||||||||||||||||||
GenPept | |||||||||||||||||||
RNA Seq Atlas | |||||||||||||||||||